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KMID : 1234920160160010036
Journal of Korean Oriental Association for Study of Obesity
2016 Volume.16 No. 1 p.36 ~ p.49
Clinical Outcomes after Modified Fasting Therapy Supplied with Gamrosu: A Retrospective Observational Study
Shin Seung-Uoo

Kim Dong-Hwan
Shin Hyun-Taeg
Oh Dal-Seok
Abstract
Objectives: Two historical evidence supported the concept of Gamrosu. The first one was Jeho-tang, a selected thirst quencher in Chosun Dynasty and the second one was Saeng- Maek-san, Dongeuibogam¡¯s recommendation as one of the qi-vigorating summer beverages. Gamrosu is a modified fasting therapy beverage which is manufactured from those two prescriptions and the carbohydrates (420.6 kcal/d). A retrospective observational study was conducted to evaluate the clinical outcomes.

Methods: Thirty-three cases were reviewed at three local Korean Medical clinics that each site¡¯s participant has finished the modified fasting for 10 consecutive days. Clinical outcomes were reviewed at pre- and post-fasting sessions by retrieving the changes of body composition, blood pressure, blood chemistries & urine tests, and subjective symptoms & fatigue scores.

Results: Demographics of the observed participants were 17 of male and 16 of female. Post-Gamrosu session, ?6.89% of body weight, ?8.97% of body fat mass were reduced with the nutrition indices being improved (P£¼0.001). ?8.72% of systolic blood pressure, ?39.86% of serum triglyceride, ?6.75% of fast blood sugar and ?8.12% of waist circumference were improved (P£¼0.05). The levels of high sensitivity C-reactive protein (?58.34%), CRP (?43.55%) and eosinophil (?21.30%) showed the significant diminished profiles (P£¼0.05). Liver/kidney functions and the standard of electrolytes were maintained within normal range in stable manners. The fatigue scale scores indicated significant lower scores.

Conclusions: Taken together, obesity-related clinical outcomes after a modified fasting therapy with Gamrosu were sufficiently feasible and the observed findings should be considered for further prospective clinical studies.
KEYWORD
Gamrosu, Modified fasting, Obesity, Metabolic syndrome, Inflammation
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